© 2005 - 2019 WebMD LLC. The most concerning side effects of Zofran include effects on the heart rhythm, a potential for birth defects and a condition known as serotonin syndrome. Available for Android and iOS devices. Extrapyramidal Reaction 8. The National Institutes of Health lists the following as common side effects. Doctors also prescribe it to pregnant women who have extreme or debilitating morning sickness. Cerner Multum, Inc. "UK Summary of Product Characteristics." This drug is more popular than comparable drugs. A myriad of women have come forward after experiencing adverse effects after taking the medication. 4. Multimedia: Slideshows, Images & Quizzes Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Common side effects associated with Zofran include headache, drowsiness, constipation and the chills. Decreased Oxygen In The Tissues Or Blood 7. Ondansetron works in the stomach to block the signals to the brain that cause nausea and vomiting. Oculogyric crisis occurred alone and in combination with other dystonic reactions. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Stevens-Johnson Syndrome 15. Side Effects. More common side effects. Ondansetron is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy.It is also used to prevent or treat nausea and vomiting after surgery. Cerner Multum, Inc. "Australian Product Information." It is also used to prevent or treat nausea and vomiting after surgery. Things to remember when you fill your prescription. Applies to ondansetron: film, solution, tablet, tablet disintegratingOther dosage forms: 1. injection solutionAlong with its needed effects, ondansetron (the active ingredient contained in Zofran) may cause some unwanted effects. Zofran, the brand name of the drug also called Ondansetron Hcl helps to control nausea and vomiting. O 0. It can be given by mouth or by injection into a muscle or into a vein. Ondansetron orally disintegrating tablet may cause drowsiness. All medications have side effects, including Zofran. Abnormal Liver Function Tests 3. 3. It is also used to prevent nausea and vomiting that may occur after surgery. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ondansetron (Zofran) is a moderately priced drug used to treat nausea and vomiting caused by chemotherapy. In fact, along with the risks of birth defects in their infants, other side effects that directly affect the mother include: In clinical trials of patients taking Zofran to prevent nausea and vomiting associated with chemotherapy, nearly a quarter of patients taking 8 mg of the drug twice daily experienced a headache. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Applies to ondansetron: film, solution, tablet, tablet disintegrating. Life Threatening Allergic Reaction 11. Many of the cases of blindness resolved from within a few minutes to approximately 28 hours. 2. If experienced, these tend to have a Severe expression 1. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. We comply with the HONcode standard for trustworthy health information -. Giant Hives 10. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Zofran (ondansetron)." Fast Heartbeat 9. Read this article to learn more about dosage and side effects. Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, or surgery. Cerenex Pharmaceuticals, Research Triangle Pk, NC. Side Effects What are the side effects of Ondansetron (Zofran)?. Zofran (ondansetron) is an antiemetic and selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting due to cancer chemotherapy and also used to prevent and treat nausea and vomiting after surgery. Headache occurred more often in the oral dissolving tablet formulation when taken with water. If experienced severely or for a … The more common side effects of ondansetron can include: In the ondansetron prescribing label information (Zofran®, Zofran ODT® package insert), the most commonly reported ondansetron (Zofran®, Zofran ODT®) side effects are shown here. Zofran Side Effects When given to a pregnant woman, Zofran can cause a wide range of birth defects. [Ref], Very common (10% or more): Headache (up to 27%), drowsiness/sedation (up to 23%), Common (1% to 10%): Dizziness, paresthesia, Uncommon (0.1% to 1%): Seizures, movement disorders/extrapyramidal reactions (oculogyric crisis/dystonic reactions, dyskinesia), Rare (0.01% to 0.1%): Grand mal seizures[Ref]. "Product Information. If you struggle with nausea … Some side effects may not be reported. Ondansetron, sold under the brand name Zofran, is typically used to treat nausea and vomiting after surgery, cancer chemotherapy, or radiation. Transient, asymptomatic increases in AST/ALT 2 times the upper limit of normal commonly occurred in patients receiving chemotherapy with cisplatin, and did not appear to be related to dose/duration of treatment. What Are Side Effects of Zofran? There are no adequate studies of Zofran in pregnant women to determine its safe and effective use during pregnancy. These side effects may go away during treatment as your body adjusts to the medicine. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. Many times, it is used for people receiving cancer treatments, such as radiation therapy or chemotherapy. At the extreme end, the use of the drug caused fetal death including miscarriage and stillbirth. Medically reviewed by Drugs.com. Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking Zofran (ondansetron). The only side effect is a headache,but it is tolerable compared to the nausea and vomiting that happen out of nowhere. There are some side effects associated with Zofran. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. Some of the dosage forms listed on this page may not apply to the brand name Zofran. Most patients were receiving concomitant chemotherapy with cisplatin. How long before a meal should you take ondansetron? Zofran is a drug with problematic side effects. 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